研究論述
張雍講座教授是中原大學的傑出研究學者,專長於仿生高分子科學、薄膜分離技術、生醫材料與化學工業程序的跨領域研究,尤其在精準醫療應用領域中取得了突出成就。張教授的研究聚焦於如何以材料科學與醫學工程來解決疾病預防、診斷與治療中的關鍵問題,透過設計分子化學與物理結構來調控生物體與材料之間的分子作用力,達到精準控制生物物質變化的功能。尤其是其開發的仿生雙離子技術,模擬自然界中生物細胞的電荷分佈,能夠有效調控免疫系統的反應,進一步提高疾病治療的精確度和效率。張教授的另一個技術突破是在薄膜技術方面,特別是多層高分子薄膜的應用。這些薄膜具有獨特的聯通孔洞結構,能夠實現快速且專一性的分子捕捉與過濾功能。這一創新技術被成功應用於減除白血球的過濾器中,成為全球領先的白血球過濾技術。張教授的減白過濾技術不僅突破了傳統方法的限制,還大幅縮短了過濾時間,提高了過濾的效率與精度。此技術在臨床應用中,已經造福超過45萬人次的輸血患者,顯著提升了輸血過程中的安全性與可靠性。在科研成果方面,張雍教授表現出卓越的學術影響力。迄今已發表273篇SCI論文,累計引用次數超過12,000次,h-index達到61,顯示出其研究在全球學術界的高度影響力。此外,張教授也擁有63項發明專利,其中26項專利已成功技術轉移與授權至業界使用,這些技術應用於提升產業競爭力,特別是在生醫材料與醫療器材的創新設計和製造領域,為台灣乃至全球的相關產業帶來了重要的技術支持。
除了在科研上的傑出成就,張教授也積極投入於人才培育工作。他迄今已指導超過160位博士、碩士研究生與學士專題生,並有67位學生的研究成果獲得各類學術獎項。這些學生在學術界與產業界皆取得了卓越的成就,成為推動相關領域發展的中堅力量。張教授在學生培育成果,不僅展現了他在學術上的影響力,同時也貢獻在未來科技人才發展的長期投入。張教授的科研成就與影響力,已多次獲得國內外重要榮譽的肯定。他多次入選全球前2%頂尖科學家名單,並獲得了包括行政院科技貢獻獎、國科會傑出研究獎、國家發明創作獎等多項重要獎項,這些榮譽不僅彰顯了他個人在科研領域的卓越表現,也反映了他對於全球科技進步所做出的重大貢獻。
研究論述總結,張雍教授的研究不僅在學術領域具有深遠的影響,也通過技術轉移和產學合作推動了相關生技產業的創新發展。其在精準醫療、薄膜技術及生醫材料方面的技術創新,為人類健康提供了突破性的解決方案,並藉由培育新一代的科技人才,持續推動全球科技進步。張教授在科研與產業之間架起了橋樑,其技術的成功應用不僅造福於學術界,也在實際應用中為國家與社會帶來了重大效益。
經驗分享
作為一名教育工作者與研究學者,我認為持續建立研究資源是科研道路上的關鍵第一步。當我剛開始進行研究時,我理解到資源的持續性對於長期的科研發展至關重要。建立資源不僅僅是尋求研究經費或設備支持,更重要的是建立穩定的合作夥伴關係,與學術界和產業界形成緊密聯繫。這不僅可以增加研究的資源來源,還能確保研究成果能夠迅速地轉化為實際應用。我透過不斷擴展國內外合作網絡,參與國際會議和合作項目,逐步建立了一個可以持續支持我研究的循環資源網絡。在我的科研生涯中,發表論文的目的並不是為了升等或提升職業地位,而是為了在學術領域中持續創新與突破。每一篇論文的發表,都是一次研究成果的展示,也是學術科研思考的一個階段性總結。我一直相信,科研的真正價值在於不斷為學術社群帶來新的觀點與思路,而非追求各種數字或指標上的成就。正是這種持續創新的理念,驅使我不斷探索新的研究方向,提出新的問題,尋找新的解決方案。我也經常鼓勵我的研究生,不要將發表論文當作終點,而是科研進程中的一個里程碑。
在培育研究人才方面,我始終秉持著啟發創新能力的理念。我的目標不僅僅是傳授知識,而是培養學生獨立思考的能力,鼓勵他們在研究中找到自己的創新點。我認為,現代社會和國家需要的是具備創新思維的科研人才,能夠應對未來重重關卡的挑戰。對我來說,每一位學生都應該被啟發去解決現實中的難題,而不僅僅是完成學術要求。透過這樣的人才培育過程,我的學生不僅能在學術領域取得突破性成果,也有機會在產業界成為創新的引領者。團隊合作與跨領域研究是現代科研中不可或缺的元素。在科研競爭日益激烈的環境中,單一學科或領域的突破已經不再足夠。跨領域的研究能夠帶來全新的視角,並且促進科研與技術的整合與應用。我在科研過程中,不斷與不同領域的專家合作,將仿生高分子技術與薄膜科學、生醫材料等領域結合,產生了許多具突破性的研究成果。這樣的跨學科合作,不僅提升了研究的深度與廣度,也增強了團隊的創造力和解決問題的能力。
科研需要投入持續的努力和規律的運作。科研成果不是一蹴可及的,它需要長時間的投入與專注。我相信,只有長期持續的研究才能產生深遠的影響力。因此,我始終保持著對研究的高度自律與嚴謹,從設計實驗到數據分析,每一個環節都要求精確無誤。正是這種持之以恆的態度,讓我在科研的道路上取得了持續的進步與突破。此外,科研的核心在於真正面對實際問題,提出具體的解決方案。研究不能脫離實際,否則很難產生真正的影響力。在研究過程中,我始終關注著實際問題的挑戰,並針對這些挑戰提出明確的解決策略。我不僅追求理論上的突破,更注重如何將這些成果應用於實際,解決真實世界中的難題。唯有這樣的研究,才能最終實現價值創造,並對社會的永續發展產生正面實質影響力。
最後,我要感謝中原大學對我一直以來的栽培與支持。正是因為學校提供的資源與環境,我才能夠專注於研究工作,取得今天的成就。我希望能繼續貢獻於科研與教育,並培養更多優秀的研究人才,為國家與社會的未來發展注入新的研發動能。
Research focus
Chair Professor Yung Chang, a distinguished scholar at Chung Yuan Christian University (CYCU), is renowned for his interdisciplinary research in biomimetic polymer science, membrane separation technology, biomedical materials, and chemical industrial processes. His outstanding achievements, particularly in the field of precision medicine, have garnered significant recognition. Professor Chang's research is centred on how materials science and biomedical engineering can address critical issues in disease prevention, diagnosis, and treatment. By designing the chemical and physical structures of materials, he aims to regulate the molecular interactions between biological substances and materials, achieving precise control over biological processes.
One of Professor Chang’s most notable innovations is his development of bio-inspired zwitterionic technology, which simulates the natural charge distribution of biological cells, effectively modulating immune system responses. This technology significantly enhances the accuracy and efficiency of disease treatment. Another groundbreaking advancement from Professor Chang is in membrane technology, particularly the application of multi-layered polymer membranes. These membranes possess a unique interconnected pore (bi-continuous) structure, enabling rapid and selective molecular capture and filtration. This innovative technique has been successfully applied in leukocyte reduction filters, positioning it as a global leader in leukocyte filtration technology. Professor Chang's method not only overcomes the limitations of traditional approaches but also dramatically reduces filtration time while improving efficiency and precision. In clinical applications, this technology has benefited over 450,000 blood transfusion patients, significantly enhancing the safety and reliability of the transfusion process.
In terms of scientific output, Professor Yung Chang has demonstrated exceptional academic influence. To date, he has published 273 SCI-indexed papers, with over 12,000 citations and an h-index of 61, reflecting his high standing within the global academic community. Additionally, Professor Chang holds 63 invention patents, 26 of which have been successfully transferred and licensed to industry. These technologies have enhanced industrial competitiveness, particularly in the fields of biomedical material innovation and medical device manufacturing, providing crucial technical support for both Taiwanese and global industries.
Beyond his remarkable research accomplishments, Professor Chang is deeply committed to nurturing talent. He has mentored over 160 graduate and undergraduate students, with 67 of his students receiving various academic awards for their research achievements. These students have gone on to excel in both academia and industry, becoming key drivers of progress in their respective fields. Professor Chang's contributions to talent development not only highlight his academic influence but also demonstrate his long-term dedication to the cultivation of future scientific leaders.
Professor Chang’s scientific achievements and impact have been recognised through numerous prestigious honours, both domestically and internationally. He has been consistently listed among the top 2% of scientists globally and has received accolades such as the Executive Yuan's Science and Technology Contribution Award, the National Science Council’s Distinguished Research Award, and the National Invention and Creation Award. These awards not only underscore his outstanding performance in the field of research but also reflect his significant contributions to global technological advancement.
In conclusion, Professor Yung Chang's research has had a profound impact on the academic world and has driven innovation in the biotechnology industry through technology transfer and academia-industry collaboration. His breakthroughs in precision medicine, membrane technology, and biomedical materials have provided transformative solutions for human health. By fostering the next generation of scientific talent, he continues to promote global technological progress. Professor Chang has successfully bridged the gap between academia and industry, with his technologies benefiting not only the academic community but also providing substantial benefits to society and the nation at large.
Experience sharing
As an educator and researcher, I believe that the continuous establishment of research resources is the critical first step on the path of scientific inquiry. When I first began my research journey, I understood that the sustainability of resources is essential for long-term research development. Building resources is not just about seeking funding or equipment but more importantly about establishing stable partnerships and forging close connections with both academia and industry. This approach not only expands the sources of research support but also ensures that research outcomes can be swiftly transformed into practical applications. Through expanding my domestic and international collaborative networks, participating in international conferences and joint projects, I have gradually built a cyclical resource network capable of continuously supporting my research. In my academic career, the purpose of publishing papers is not to gain promotion or enhance my professional status but to consistently innovate and make breakthroughs in the academic field. Each published paper represents a display of research achievements, a periodic summary of scholarly inquiry. I have always believed that the true value of research lies in continually bringing new perspectives and ideas to the academic community, rather than pursuing numerical targets or research index. It is this mindset of continuous innovation that drives me to explore new research directions, ask new questions, and seek new solutions. I frequently encourage my students not to view publishing a paper as the end goal but as a milestone in the process of scientific discovery.
When it comes to nurturing research talent, I have always adhered to the principle of inspiring innovative thinking. My goal is not merely to impart knowledge but to cultivate my students’ ability to think independently and to encourage them to find their own points of innovation in their research. I believe that modern society and nations require research talents equipped with innovative thinking, capable of tackling the many challenges that lie ahead. To me, every student should be inspired to solve real-world problems, rather than just fulfilling academic requirements. Through this process of talent cultivation, my students not only achieve breakthrough results in the academic world but also have the opportunity to become leaders of innovation in industry. Teamwork and interdisciplinary research are indispensable elements in modern scientific inquiry. In an increasingly competitive research environment, breakthroughs in a single discipline are no longer sufficient. Interdisciplinary research can bring new perspectives and foster the integration and application of scientific knowledge and technology. Throughout my research journey, I have continuously collaborated with experts from different fields, combining biomimetic polymer technologies with membrane science and biomedical materials, resulting in many breakthrough research outcomes. Such interdisciplinary collaborations not only deepen and broaden the scope of research but also enhance the team’s creativity and problem-solving abilities.
Research requires sustained effort and regular operation. Scientific achievements do not happen overnight; they require long-term dedication and focus. I firmly believe that only through continuous research can we generate far-reaching impact. Therefore, I have always maintained a high level of self-discipline and rigour in my research, demanding precision in every aspect, from experimental design to data analysis. It is this persistent attitude that has allowed me to make continuous progress and breakthroughs on my research journey. Moreover, the core of research lies in addressing real-world problems and proposing concrete solutions. Research should not be disconnected from reality; otherwise, it is difficult to create genuine impact. Throughout the research process, I have always focused on the challenges of practical issues and formulated clear strategies to tackle them. I strive not only for theoretical breakthroughs but also for ways to apply these results to real-world problems, solving real-world challenges. Only through such research can we ultimately create value and generate positive, substantive impacts on the sustainable development of society.
Lastly, I want to express my gratitude to Chung Yuan Christian University for the cultivation and support it has provided me over the years. It is because of the resources and environment offered by the university that I have been able to focus on my research and achieve the success I enjoy today. I hope to continue contributing to research and education and to cultivate more outstanding research talents, injecting new research momentum into the future development of the nation and society.